recombinant murine klotho (R&D Systems)
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recombinant murine klotho
Recombinant Murine Klotho, supplied by R&D Systems, used in various techniques. Bioz Stars score: 94/100, based on 57 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/recombinant+klotho+protein/Recombinant+Mouse+Klotho+(aa+35-982)+Protein%2C+CF/10__1161_slash_jaha__125__045175-59-13-23
Average 94 stars, based on 57 article reviews
Recombinant Murine Klotho, supplied by R&D Systems, used in various techniques. Bioz Stars score: 94/100, based on 57 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/recombinant+klotho+protein/Recombinant+Mouse+Klotho+(aa+35-982)+Protein%2C+CF/10__1161_slash_jaha__125__045175-59-13-23
Average 94 stars, based on 57 article reviews
recombinant murine klotho - by Bioz Stars,
2026-09
94/100 stars
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Recombinant:Article Title: Aging Impairs the Capacity of Cardiac Functional Recovery Following Endotoxemia: Modulation of Myocardial Klotho Level for Remedy. Article Snippet: Introduction: Endotoxemic/septic cardiac dysfunction occurs frequently in elderly patients undergoing major surgery and contributes to postsurgery morbidity and mortality.. This study evaluated the effect of aging on cardiac functional recovery following endotoxemia and explored therapeutic approaches for promotion of the recovery.. Methods: A small dose of endotoxin (0.5 mg/kg, iv) was administered to young adult (3-4 mo) and old (18-22 mo) mice with or without subsequent treatment with recombinant interleukin-37 (IL-37, 50 mg/kg, iv) or recombinant Klotho (10 mg/kg, iv). Article Title: Klotho Improves Cardiac Function by Suppressing Reactive Oxygen Species (ROS) Mediated Apoptosis by Modulating Mapks/Nrf2 Signaling in Doxorubicin-Induced Cardiotoxicity Article Snippet: Several rats were exposed to DOX (3 mg/kg, Sigma-Aldrich) by intraperitoneal injections (single dose of DOX every another day for total three injections) [ ]. .. Article Title: Klotho relieves inflammation and exerts a cardioprotective effect during renal ischemia/reperfusion-induced cardiorenal syndrome. Article Snippet: .. As previously performed, we treated animals with Article Title: Klotho mitigates diquat-induced myocardial injury in rats by activating Nrf2/ARE-mediated suppression of oxidative stress Article Snippet: H9c2 cardiomyocytes were obtained from the American Type Culture Collection (ATCC; Manassas, VA, USA) and cultured in Dulbecco’s Modified Eagle Medium (DEME; 11965175, Gibco, USA) containing 10% fetal bovine serum (A3382101, Gibco, USA) and 1% penicillin-streptomycin (15140148, Gibco, USA) at 37°C in a humidified atmosphere containing 5% CO 2 . .. To induce oxidative injury, cells were treated with 50 μM DQ (45422, Sigma-Aldrich, USA) for 24 h. For Klotho intervention, cells were treated with 1 μg/mL Article Title: Klotho Reduces Necroptosis by Targeting Oxidative Stress Involved in Renal Ischemic-Reperfusion Injury. Article Snippet: .. For the therapeutic investigation, a single dose of Article Title: Klotho Regulates Retinal Pigment Epithelial Functions and Protects Against Oxidative Stress Article Snippet: RPE functional assays For the phagocytosis assays, the RPE cells were grown to confluency for 20 h on poly- d -lysine (2 μg/cm 2 , BD Biosciences) and laminin-coated (4 μg/ml, Sigma-Aldrich) 96-well plates (50,000 cells/well) in EpiCM medium without serum. .. Cultures were then incubated with Enzyme-linked Immunosorbent Assay:Article Title: Aging Impairs the Capacity of Cardiac Functional Recovery Following Endotoxemia: Modulation of Myocardial Klotho Level for Remedy. Article Snippet: Introduction: Endotoxemic/septic cardiac dysfunction occurs frequently in elderly patients undergoing major surgery and contributes to postsurgery morbidity and mortality.. This study evaluated the effect of aging on cardiac functional recovery following endotoxemia and explored therapeutic approaches for promotion of the recovery.. Methods: A small dose of endotoxin (0.5 mg/kg, iv) was administered to young adult (3-4 mo) and old (18-22 mo) mice with or without subsequent treatment with recombinant interleukin-37 (IL-37, 50 mg/kg, iv) or recombinant Klotho (10 mg/kg, iv). Incubation:Article Title: Klotho inhibits angiotensin II-induced cardiomyocyte hypertrophy through suppression of the AT1R/beta catenin pathway. Article Snippet: Accepted Manuscript Klotho inhibits angiotensin II-induced cardiomyocyte hypertrophy through suppression of the AT1R/beta catenin pathway Liangzhu Yu, Wei Meng, Jieqiong Ding, Menglin Cheng PII: S0006-291X(16)30342-4 DOI: 10.1016/j.bbrc.2016.03.029 Reference: YBBRC 35461 To appear in: Biochemical and Biophysical Research Communications Received Date: 19 February 2016 Accepted Date: 8 March 2016 Please cite this article as: L. Yu, W. Meng, J. Ding, M. Cheng, Klotho inhibits angiotensin II-induced cardiomyocyte hypertrophy through suppression of the AT1R/beta catenin pathway, Biochemical and Biophysical Research Communications (2016), doi: 10.1016/j.bbrc.2016.03.029.. This is a PDF file of an unedited manuscript that has been accepted for publication.. As a service to our customers we are providing this early version of the manuscript. Article Title: Klotho Regulates Retinal Pigment Epithelial Functions and Protects Against Oxidative Stress Article Snippet: RPE functional assays For the phagocytosis assays, the RPE cells were grown to confluency for 20 h on poly- d -lysine (2 μg/cm 2 , BD Biosciences) and laminin-coated (4 μg/ml, Sigma-Aldrich) 96-well plates (50,000 cells/well) in EpiCM medium without serum. .. Cultures were then incubated with Phagocytosis Assay:Article Title: Klotho Regulates Retinal Pigment Epithelial Functions and Protects Against Oxidative Stress Article Snippet: RPE functional assays For the phagocytosis assays, the RPE cells were grown to confluency for 20 h on poly- d -lysine (2 μg/cm 2 , BD Biosciences) and laminin-coated (4 μg/ml, Sigma-Aldrich) 96-well plates (50,000 cells/well) in EpiCM medium without serum. .. Cultures were then incubated with |
